昆虫杆状病毒基因组学研究进展

摘要/Abstract

摘要： 杆状病毒（Baculoviruses）是一类在自然界中专一性感染节肢动物的共价闭合双链环状DNA病原微生物。由于杆状病毒的宿主特异性高，其作为无公害生物杀虫剂在生物防治方面发挥重大作用。此外，杆状病毒已被开发成为高效的真核表达载体，广泛应用于药物研发、疫苗生产等领域，并作为基因治疗载体用于疾病的基因治疗。综述了获得全基因组序列的昆虫杆状病毒类别及其序列特征，以及昆虫杆状病毒基因组中的主要功能基因，包括RNA转录相关基因、DNA复制相关基因、结构蛋白基因等，也对其应用做了较为详尽的阐述。

关键词: 昆虫杆状病毒, 基因组学, 功能基因, 应用

梁振普，刘雅静，张小霞，李鹏娟，王亮，张俊庆. 昆虫杆状病毒基因组学研究进展[J]. 河南农业科学, 2018, 47(9): 1-7.

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