关键词: 猪细小病毒, 生物学特性, 发病机制, 遗传变异

Abstract:  Porcine parvovirus(PPV) is the most common and important infectious agents causing porcine reproductive failure．All the time，it was thought that PPV had low genetic variance，and its harmful effect on pig industry could be well-controlled by vaccination．However，subsequent studies found that the diver sity of PPV was much greater than previously anticipated． Some of the new highly virulent，which can’tbe neutralized effectively by antisera raised agains told classical PPV vaccine strains，were isolated．The pur pose of this review is to summarize the recent results of PPV research，update the present understanding of PPV biology，and reveal the potential risks of new PPV strains and their harm to pig industry under the pressure of selection，which will provide reference for formulating effective prevention and control strate gies of PPV．

Key words: Porcine parvovirus, Biological characteristics, Pathogenesis, Genetic variation