参考文献:
[1] Qiu Y,Nguyen K D,Odegaard J I,et al.Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat[J].Cell,2014,157(6):1292-1308.
[2]Brestoff J R,Kim B S,Saenz S A,et al.Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity[J].Nature,2015,519(7542):242-246.
[3]Lee M W,Odegaard J I,Mukundan L,et al.Activated type 2 innate lymphoid cells regulate beige fat biogenesis[J].Cell,2015,160(1/2):74-87.
[4]Gregoire F M,Smas C M,Sul H S,et al.Understanding adipocyte differentiation[J].Physiol Rev,1998,78(3):783-809.
[5]鞠大鹏,詹丽杏.脂肪细胞分化及其调控的研究进展[J].中国细胞生物学学报,2010,32(5):690-695.
[6]Guo L,Li X,Tang Q Q,et al.Transcriptional regulation of adipocyte differentiation: A central role for CCAAT/enhancer-binding protein (C/EBP) β[J].J Biol Chem,2015,290(2):755-761.
[7]Nam D,Guo B,Chatterjee S,et al.The adipocyte clock controls brown adipogenesis through the TGF-β and BMP signaling pathways[J].J Cell Sci,2015,128(9):1835-1847.
[8]Luo H,Zhou Y,Hu X,et al.Activation of PPARγ2 by PPARγ1 through a functional PPRE in transdifferentiation of myoblasts to adipocytes induced by EPA[J].Cell Cycle,2015,14(12):1830-1841.
[9]肖荣,辛友志.可变剪接事件在脂肪细胞分化中的影响[J].聊城大学学报(自然科学版),2018,31(1):83-88.
[10]Hardman C,Ogg G.Interleukin33,friend and foe in type-2 immune responses[J].Curr Opin Immunol,2016,42:16-24.
[11]Klemenz R,Hoffmann S,Werenskiold A K.Serum and oncoprotein-mediated induction of a gene with sequence similarity to the gene encoding carcinoembryonic antigen[J].Proc Natl Acad Sci USA,1989,86(15):5708-5712.
[12]Baba Y,Maeda K,Yashiro T,et al.GATA2 is a critical transactivator for the human IL1RL1/ST2 promoter in mast cells/basophils:Opposing roles for GATA2 and GATA1 in human IL1RL1/ST2 gene expression[J].J Biol Chem,2012,287(39):32689-32696.
[13]Schmitz J,Owyang A,Oldham E,et al.IL-33,an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines[J].Immunity,2005,23(5):479-490.
[14]Sanada S,Hakuno D,Higgins L J,et al.IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system[J].J Clin Invest,2007,117:1538-1549.
[15]Mildner M,Storka A,Lichtenauer M,et al.Primary sources and immunological prerequisites for sST2 secretion in humans[J].Cardiovasc Res,2010,87(4):769-777.
[16]Kunze M M,Benz F,Brauβ T F,et al.sST2 translation is regulated by FGF2 via an hnRNP A1-mediated IRES-dependent mechanism[J].Biochim Biophys Acta,2016,1859(7):848-859.
[17]Zhao J,Chen Q,Li H,et al.Lysophosphatidic acid increases soluble ST2 expression in mouse lung and human bronchial epithelial cells[J].Cell Signal,2012,24(1):77-85.
[18]Kakkar R,Hei H,Dobner S,et al.Interleukin 33 as a mechanically responsive cytokine secreted by living cells[J].J Biol Chem,2012,287(9):6941-6948.
[19]Chackerian A A,Oldham E R,Murphy E E,et al.IL-1 receptor accessory protein and ST2 comprise the IL-33 receptor complex[J].J Immunol,2007,179(5):2551-2555.
[20]Kakkar R,Lee R T.The IL-33/ST2 pathway:Therapeutic target and novel biomarker[J].Nat Rev Drug Discov,2008,7(10):827-840.
[21]Pascual-Figal D A,Januzzi J L.The biology of ST2:The international ST2 consensus panel[J].Am J Cardiol,2015,115(7):3B-7B.
[22]司原成,王晓芳,汪戈力,等.营养性肥胖之免疫机制研究进展[J].中国实验方剂学杂志,2016,22(9):40-45.
[23]Schmieder A,Multhoff G,Radons J.Interleukin-33 acts as a pro-inflammatory cytokine and modulates its receptor gene expression in highly metastatic human pancreatic carcinoma cells[J].Cytokine,2012,60(2):514-521.
[24]Zeyda M,Wernly B,Demyanets S,et al.Severe obesity increases adipose tissue expression of interleukin33 and its receptor ST2,both predominantly detectable in endothelial cells of human adipose tissue[J].Int J Obes (Lond),2013,37(5):658-665.
[25]Ragusa R,Cabiati M,Guzzardi M A,et al.Effects of obesity on IL-33/ST2 system in heart,adipose tissue and liver:Study in the experimental model of Zucker rats[J].Exp Mol Pathol,2017,102(2):354-359.
[26]Moro K,Yamada T,Tanabe M,et al.Innate production of T-H2 cytokines by adipose tissue-associated c-Kit+ Sca-1+ lymphoid cells[J].Nature,2010,463:540-544.
[27]Molofsky A B,Nussbaum J C,Liang H E,et al.Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages[J].J Exp Med,2013,210(3):535-549.
[28]Duffen J,Zhang M,Masek-Hammerman K,et al.Modulation of the IL-33/IL-13 axis in obesity by IL-13Rα2[J].J Immunol,2018,200(4):1347-1359.
[29]Flach M,Diefenbach A.Adipose tissue:ILC2 crank up the heat[J].Cell Metab,2015,21(2):152-153.
[30]Nguyen K D,Qiu Y,Cui X,et al.Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis[J].Nature,2011,480:104-108.
[31]Wu D,Molofsky A B,Liang H E,et al.Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis[J].Science,2011,332:243-247.
[32]Wood I S,Wang B,Trayhurn P.IL-33,a recently identified interleukin-1 gene family member,is expressed in human adipocytes[J].Biochem Biophys Res Commun,2009,384(1):105-109.
[33]Odegaard J I,Lee M W,Sogawa Y,et al.Perinatal Licensing of Thermogenesis by IL-33 and ST2[J].Cell,2017,171(7):1707. |