关键词: 长链非编码RNA, 调节机制, RNA编辑, RNA修饰

Abstract: Long non-coding RNAs(lncRNAs) are non-coding transcripts that lack an open reading frame and are more than 200 nt in length.They are large in absolute quantity and variety and have obvious cell specificity in expression patterns.They play a variety of biological functions through base pairing with DNA or RNA or binding to proteins via the advanced structure of RNA,thus constituting a complex and delicate molecular regulatory network.In this paper,combined with the research findings of lncRNA in recent years,based on expounding the research progress of molecular mechanism of lncRNA,the related research of lncRNA in animal production performance and animal growth and development was briefly described,to provide a reference for further research on the biological regulation function of lncRNA,and also provide the scientific basis for the application of lncRNA in animal husbandry.

Key words: Long non-coding RNA, Regulatory mechanism, RNA editing, RNA modification