Ligusticum chuanxiong Hort.is a famous Dao-di herb in Sichuan,due to its high concentration of cadmium,the safety and effectiveness of its medicinal quality have attracted much attention.How to reduce the cadmium content in the Ligusticum chuanxiong Hort.has became one of the keys to the development of the Ligusticum chuanxiong industry.The paper described the cadmium pollution situation of Ligusticum chuanxiong and the law of cadmium absorption and accumulation,and then emphatically analyzed the influence factors of cadmium pollution of Ligusticum chuanxiong Hort.and the measures to reduce the cadmium content.Under the condition that the soil remediation technology cannt realize the production of Ligusticum chuanxiong safely,in a short time,suggesting that the cultivar of Ligusticum chuanxiong with low concentration of cadmium can be selected through the combination of molecular technology and radiation mutagenesis technology,hoping to provide reference for solving the problem of heavy metal pollution caused by Ligusticum chuanxiong.