To study the growth development law of Dezhou donkey,200 donkeys(100 males and 100 females) were selected randomly. Their body weight,height at withers,body length,heart girth and cannon circumference were measured at the age of 0,3,6,12,24 months,respectively.Then their growth curves were fitted by Betalanffy,Gompertz and Logistic non-linear models,respectively.The results showed that all the three models could fit the growth curves of body weight and body sizes of Dezhou donkey effectively(R²<0.850).Among them,the Bertalanffy model had the best fitting effect on body weight,height at withers,body length,heart girth(R²>0.910),and the fitting results were nearest to the measured values.Through the Bertalanffy model,the predicted mature weights of male and female donkeys were 248.51 kg and 221.60 kg,respectively; the predicted inflexion weights were 73.63 kg and 65.66 kg,respectively;the predicted inflexion month ages were 2.43 and 1.95,respectively.