Field experiment was carried out using Zhongyan 100，the main cultivar as material，to investigate the effects of transplanting time and harvesting time on economic characters and quality characteristics of upper six leaves of flue-cured tobacco.The results showed that the transplanting time and harvesting time significantly affected the economic traits of upper six leaves,and there was a very significant interaction effect.The effect of transplanting time on yield and output value was greater than that of harvesting time,while the harvesting time had a greater influence on the proportion of superior  tobacco，single leaf weight and average price of upper six leaves.Transplanting from April 25 to May 5 gave rise to higher yield and output value.Delaying harvest by 6 d and 12 d resulted in no difference in average price,but it was significantly higher than other treatments,with the proportion of superior tobacco increased significantly by 10.66% and 15.39% respectively compared with the normal harvest.The transplanting time was closely related to strong-aroma style of upper six flue-cured tobacco leaves,and the transplanting time no later than May 5 was beneficial to the display of the strong-aroma style of upper six leaves.With the delay of the transplanting time from April 15 to May 5,the potassium-chlorine ratio of upper six leaves increased,and the flammability was better.The content of neutral aroma components was highest when transplanting tobacco from April 25 to May 5.The harvesting time had a great influence on the quality of upper six leaves,as harvesting time delayed,the protein content,starch content,sugar-alkali ratio of upper six leaves decreased,and tended to be optimum when the harvesting time was delayed for 12 days.The sensory quality of upper six leaves showed an increasing trend as a whole as harvesting time delayed,and was the best under a delay of 12 days with significant increase of total amount of neutral aroma components.Comprehensive analysis showed that transplanting from April 25 to May 5 and harvesting with 6-12 days delayed were conducive to improvement of economic characters,quality,and the display of strong-aroma style of upper six tobacco leaves in central Henan．